Dr. Priya Narayan

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Dr. Priya Narayan

Associate Professor

M.Sc (Microbiology) M.Phil (Biotechnology) Ph.D (Structural Biophysics)

Department of Biotechnology Engineering

DOJ SIRMVIT

  • 18/8/2006

Teaching Experience

  • 18 Yrs

Contact Faculty

Industry

  • 1 Yrs.

Research Experience

  • 15 Yrs

Specialization

  • Microbiology
  • Biophysics

Research Interest

  • Peptide chemistry
  • Structural Biophysics
  • Microbiology
  • Phytochemistry

Research Topics

  • Structural Studies Of Amyloid Beta Fragments With Small Molecules: Its Implications In Alzheimer’s Disease
  • Bioaccumulation Assessment Of Lead Contamination In Fenugreek Leaves And Their Associated Health Risks- A Comparitive Study & Design Of A Filteration Unit Using Kitchen Waste And Assessment Of Its Effectiveness As Individual Components And In Combination
  • Isolation And Characterization Of Secondary Metabolites From Algae
  • Bioremediation Of Heavy Metals From Contaminated Lakes Using Algae And Kitchen Waste
  • In silico, In vitro and Ex vivo studies of Caesalpinia bonducella and their therapeutic implications.

Research Topics

  • Structural Studies Of Amyloid Beta Fragments With Small Molecules: Its Implications In Alzheimer’s Disease
  • Bioaccumulation Assessment Of Lead Contamination In Fenugreek Leaves And Their Associated Health Risks- A Comparitive Study & Design Of A Filteration Unit Using Kitchen Waste And Assessment Of Its Effectiveness As Individual Components And In Combination
  • Isolation And Characterization Of Secondary Metabolites From Algae
  • Bioremediation Of Heavy Metals From Contaminated Lakes Using Algae And Kitchen Waste
  • In silico, In vitro and Ex vivo studies of Caesalpinia bonducella and their therapeutic implications.

Courses Handled

  • Microbiology Theory And Lab,
  • Clinical Biochemistry Lab,
  • Food Process Technology,
  • Clinical And Pharmaceutical BT,
  • Metabolic Engineering,
  • Advanced Microbiology

Funded Projects

On-going projects

  • Bioaccumulation Assessment Of Lead Contamination In Fenugreek Leaves And Their Associated Health Risks- A Comparitive Study & Design Of A Filteration Unit Using Kitchen Waste And Assessment Of Its Effectiveness As Individual Components And In Combination
  • Isolation And Characterization Of Secondary Metabolites From Algae
  • Bioremediation Of Heavy Metals From Contaminated Lakes Using Algae And Kitchen Waste
  • Pharmacological Studies of Caesalpinia bonducella

 Past Funding

  • In Vitro and Ex Vivo Pharmacological Studies of CaesalpiniaBonducella Extract Bristol Myers Squibb for 3.46 Lakhs
  • 35 INR lakhs (BIRAC Support to MVIT 68.50 lakhs INR.), “Bench scale production of Snowflake Cordyceps and Cordyceps militaris through solid state and submerged fermentation, respectively for nutraceutical applications”, BIPP-BIRAC (DBT-GoI),2016.
  • KSCST project proposal entitled ““Insitu Solution for Heavy metal contaminated Lake Waters of Bengaluru” was approved and funded ( 7000/- ) for 40th Series of student projects programme : 2016 – 2017  by Karnataka state council for science and technology, IISc, Bangalore –12.
  • KSCST project titled “Extraction and screening of glucansucrase (glucosyltransfarase) specific inhibitor from plant source to prevent dental caries”. was awarded “project of the year” at the state level seminar presentation held at BLDE Association‘s Vachana Pitamaha Dr. P. G. Halakatti College of Engineering and Technology, Vijayapura (Bijapur) on 19th and 20th August 2016.
  • KSCST project titled “A novel approach in utilization of Flower Waste from Chikkaballapur Market towards development of value added products won the Project of the Year award in 2014.
  • Part of the project“Structural Investigation of Amyloid peptide fragments Implicated in Alzheimer’s Disease”(DST Funded Project  Rs. 16.33 Lakhs – Period: 2012-2015; Collaborative Project with NMRC, IISc, Bangalore) actively associated with structural work using CD and N MR

Research Publications

  • V Prasad, Jagadeesh Kumar D, Narayan P, Govindaraju M, Nagendra H G, Imaging in diagnosis and management of COVID 19: A short review. IP Int J Med Microbiol Trop Dis 2020;6(4):193-197
  • Govindaraju M, Jagadeesh Kumar D, Narayan P, Rao K R S S, Rao K S, Spectroscopic and insilico Studies of Aβ
  • (1-16) on Copper induced conformational changes in Poly (dG-dC). Poly ( dG-dC) [Poly(GC)] DNA sequence: Implications in Alzheimer’s diseaseIP Indian J Neurosci 2020;6(3):174-182
  • Disruption of Biofilms by the action of Peptides from Human Placental Extract, Bandyopadhyay, Sambit || Narayan, Priya || Selvan, Arul || Nagendra HG, IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 17, Issue 11 Ver. 5 (November. 2018), PP 30-34
  • Evaluation of Pharmacological Properties of Caesalpiniabonducella Seed and Shell Extract Pharmacognosy Journal H G Nagendra, Vigasini Subbiah, Pannaga Nagaraja, Priya Narayan 2019; 11(1)
  • Computational Studies to Decipher the Plausible Inhibition of Type III Secretion System (T3ss) ATPases Involved in Bacterial Motility and Virulence, Jagadeesh Kumar.D*, SnehaPaturi, s kiranchandrika, P Ashwathi, Priya Narayan, H G Nagendra Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences ,– April RJLBPCS 5(2) Page No.1037
  • Priya Narayan, Jagadeesh Kumar D, Govinda Raju, H G Nagendra, K. R. K. Easwaran “CD and Computational studies on Aβ (1-16) suggests determinants of ligand binding and plausible prevention of metal induced toxicity via Betaine like molecules”, Journal of Applied Biology & Biotechnology 5 (03); 2017: 030-038
  • “In Silico Docking Analysis of Amyloid Precursor Protein Intracellular Domain AICD- Peptide with Neuronal Cytoplasmic and Nuclear Membrane Proteins and Its Relevance in Neuronal Death and AD Pathogenesis.” Jagadeesh Kuamr. D, Mainak Mondal, Kapil Kumar Mehta, Priya Naryan, H G Nagendra “Indian Journal of Neurosciences” 3 Issue. 3, September,2017
  • Priya Narayan, D. Jagadeesh Kumar M. Govindaraju, K. N. ShashankaRao, H. G. Nagendra and K. R. K. Easwaran published the paper titled “Conformational studies of Aβ (1-12) with metals and small molecules suggests plausible disruption of aggregation” in the International Journal of Research Studies in Biosciences (IJRSB), Volume 2, Issue 11, December 2014, PP 28-35, ISSN 2349-0365
  • Shruthila, Priya Narayan, D. Jagadeesh Kumar, and H. G. Nagendra: Docking Studies of Plant Polyphenols with Aβ Fragments Suggests Determinants That Enable Design of Inhibitors towards Preventing Aggregation Events during Alzheimer’s. International Journal of Pharmaceutical Sciences and Drug Research 2013; 5(4): 170-174
  • Narayan P, Krishnarjuna B, Vishwanathan V, Jagadeesh Kumar D, Babu S, Ramanathan KV, Easwaran KR, Nagendra HG, Raghothama S, (2013) Does Aluminium Bind to Histidine? An NMR Investigation of Amyloid β 12 and Amyloid β 16 Fragments ChemBiol Drug Des.,82, 48-59

Publications under Review

  • Network Based Systems Biology Approaches Of Alzheimer’s Disease And Its Key Neighboring Pathways Reveal The Potential Role Of Kinases And Phosphatases On Tau Mediated Pathology of AD Progression, Jagadeesh Kumar.D,  Priya Narayan & H G Nagendra
  • Interactions of Amyloid Precursor Protein Intracellular Domain (Aicd) With Copper and Dna Fragment Reveal Conformational Changes That Triggers Alzheimer’s Disease (Ad), D. Jagadeesh Kumar, M. Govindaraju, Priya Narayan, H. G Nagendra, Kss Rao K.S. Krk Easwaran and Jagannatha Rao
  • Interaction Of Copper (II) with (Ccg) 12 Repeats Sequence: Spectroscopic And Computational Modeling Insightsinteraction Of Copper (Ii) With (Ccg) 12 Repeats Sequence: Spectroscopic and Computational Modeling Insights
  • Small Molecule Activators of Pp2a Suggests Controlled Tau Phosphorylation as A Novel Mode of Therapy For Alzheimer’s Disease” Has Been Successfully – Journal Of Computational Biology. D. Jagadeesh Kumar, Priya Narayan, H.G. Nagendra
  • Study Of Potential Drug Target Aicd Central 12 Residue Peptide Stretch And Its Interactions With Metals And Polyphenols: An Nmr And Molecular Docking Analysis., Dillip Senapathi, D. Jagadeesh Kumar, Priya Narayan, H.G. Nagendra, Govindaraju M, K.R.K Easwaran, K.V. Ramanathan, S. Raghothama

Membership of Professional Bodies

  • Life Member of National Magnetic Resonance Society (NMRS)
  • Associate Life member of Indian academy of neurosciences, [IAN] India

Honours & Achievements

Birac Innovators Award 2021

Dr Priya Narayan, Associate professor, Dept. of Biotechnology, Sir MVIT and Dr. Mousami Mondal, and Team from Mallipathra Nutraceutical Private Limited, Incubatee @ Sir M Visvesvaraya Institute of Technology for winning the BIRAC Innovator award -2020 during the award ceremony of the “Global Bio India 2021 held on 3rd March 2021.

About Innovation: The Company has developed a novel process for growing the world’s costliest endangered medicinal mushroom cordyceps in an artificial environment which grows much faster than the naturally available cordyceps. The innovation involves   a process of growing these mushrooms on both vegetarian and non-vegetarian substrates which is on par with the naturally grown Cordyceps in terms of active ingredients. The company has developed various formulations like health drinks, infusions, capsules etc., comprising of cordyceps for nutraceutical applications

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